Pharmaceutical Peptide CAS No. 129954-34-3 Top Quality Selank

Model NO.: API Customized: Customized Suitable for: Adult Purity: >98% Mf: C33h57n11o9 Appearance: White Powder Type: Pharmaceutical Intermediates Shelf Life: 2 Years Transport Package: Box Origin: Shanghai Powder: Yes Certification: GMP, HSE, ISO 9001, USP, BP State: Solid CAS No: 129954-34-3 Other Names: Selank Place of Origin: Shang Hai China (Mainland) The Purity: Over 98% Shipping Method: FedEx, DHL, EMS or by Air Specification: 5mg/vial                            Pharmaceutical  Peptide CAS No. 129954-34-3 Top Quality Selank
Quick Details

CAS No.:	129954-34-3	Other Names:	Selanc; L-threonyl-L-lysyl-L-prolyl-L-arginyl-L-prolylglycyl-L-Proline	MF:	C33H57N11O9
EINECS No.:	N/A	Place of Origin:	Hubei, China (Mainland)	Type:	Vitamins, Amino Acids and Coenzymes
Grade Standard:	Medicine Grade, Tech Grade	Usage:	Animal Pharmaceuticals
		Purity:	99%min	Product Name:	Selank
Appearance:	White Powder	CAS:	129954-34-3	Assay:	98.0% Min
Application:	anxiolytic peptide	Certificate:	ISO	Molecular Weight:	751.89
Chemical Name:	selank	Packing:	vials or bags	Storage:	2 years

Description    
 

roduct Name	Selank	Other Name	Selanc; L-threonyl-L-lysyl-L-prolyl-L-arginyl-L-prolylglycyl-L-Proline
Appearance	white powder	CAS No.	129954-34-3
Purity	98%min	M.W	751.89
		M.F	C33H57N11O9
Structure

 
 
 
Application
 
Selank is a synthetic analogue of the immunomodulatory peptide tuftsin; as such, it mimics many of its effects. It has been shown to modulate the expression of Interleukin-6 (IL-6) and affect the balance of T helper cellcytokines.[1] It has been shown to influence the concentration of monoamine neurotransmitters[2] and induce metabolism of serotonin.[3][4] Selank has also been found to rapidly elevate the expression of brain-derived neurotropic factor (BDNF) in the hippocampus of rats.[5]
Selank, as well as a related peptide drug, Semax, have been found to inhibit enzymes involved in the degradation of enkephalins and other endogenous regulatory peptides, and this action may be involved in their effects.[6] It has also been found to affect the activity of carboxypeptidase H and phenylmethylsulfonylfluoride-inhibitedcarboxypeptidase in rat nervous system tissue.[7]
Selank has been found to produce antidepressant-like effects in animal models of depression and anhedonia.[8]
Clinical trials
In clinical trials, the drug has shown to provide a sustained nootropic and anxiolytic effect which is useful for the treatment of generalized anxiety disorder (GAD).Selank has an advantage over traditional anxiety treatments,, as it has no sedating or negative cognitive side effects and no associatedaddiction or withdrawal problems.
Selank is closely related to another nootropic drug, Semax, also developed by the Institute of Molecular Genetics in Russia. This drug is currently available in Russian and Ukrainian pharmacies.[9]
As with all lipophilized peptides, it needs refrigeration to remain stable within sterile water solutions, such as bacteriostatic water concentrations.

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